Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7458773 | 0.79 | ALDH1A1 (0.35) | ALDH1A1HSD17B10 | |
| SCHEMBL21712222 | 0.79 | PI4KA (0.36) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL1193025 | 0.76 | PI4KA (0.34) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL5544035 | 0.76 | ALDH1A1 (0.33) | ALDH1A1HSD17B10 | |
| SCHEMBL30002773 | 0.76 | MAPT (0.41) | ALDH1A1HSD17B10 | |
| SCHEMBL30904069 | 0.76 | PI4KA (0.34) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL6129371 | 0.76 | MAPT (0.41) | ALDH1A1HSD17B10 | |
| SCHEMBL22026196 | 0.76 | PI4KA (0.34) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL5544044 | 0.76 | ALDH1A1 (0.33) | ALDH1A1HSD17B10 | |
| SCHEMBL30949588 | 0.76 | PI4KA (0.34) | CYP3A4TSHRPI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022012622-A1 | DEGRADATION OF (EGFR) BY CONJUGATION OF EGFR INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2022-01-20 | — | — | WO | disclosed |
| WO-2020132384-A1 | THIENOPYRIDINE INHIBITORS OF RIPK2 | CELGENE CORPORATION (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-1998023612-A1 | 2-IMIDAZOLINYLAMINOBENZOTHIAZOLE COMPOUNDS USEFUL AS ALPHA-2 ADRENOCEPTOR AGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 1998-06-04 | — | — | WO | disclosed |