Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6129371 | 1.00 | MAPT (0.41) | MAPTNPC1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL7458773 | 0.79 | ALDH1A1 (0.35) | MAPTNPC1ALDH1A1HSD17B10RAB9A | |
| SCHEMBL6129362 | 0.76 | ALDH1A1 (0.33) | ALDH1A1HSD17B10TRPM5 | |
| SCHEMBL8580366 | 0.76 | CYP3A4 (0.34) | ALDH1A1HSD17B10 | |
| SCHEMBL5544044 | 0.76 | ALDH1A1 (0.33) | NPC1ALDH1A1HSD17B10RAB9AATM | |
| SCHEMBL15278576 | 0.76 | ALDH1A1 (0.33) | ALDH1A1HSD17B10 | |
| SCHEMBL11684574 | 0.76 | PI4KA (0.34) | MAPTNPC1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL31390036 | 0.76 | ALDH1A1 (0.33) | ALDH1A1HSD17B10 | |
| SCHEMBL5544035 | 0.76 | ALDH1A1 (0.33) | NPC1ALDH1A1HSD17B10RAB9AL3MBTL1 | |
| SCHEMBL17591354 | 0.76 | ALDH1A1 (0.31) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |