Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582956 | 0.93 | ALDH1A1 (0.34) | ALDH1A1TSHRKDM4EHPGDMAPT | |
| SCHEMBL8583887 | 0.92 | ALDH1A1 (0.34) | ALDH1A1TSHRKDM4EHPGDMAPT | |
| SCHEMBL8581511 | 0.89 | KDM4E (0.36) | ALDH1A1TSHRKDM4EHPGDMAPT | |
| SCHEMBL8580447 | 0.87 | KDM4E (0.36) | ALDH1A1TSHRKDM4EHPGDMAPT | |
| SCHEMBL8581031 | 0.86 | CMA1 (0.39) | ALDH1A1TSHRKDM4EHPGDMAPT | |
| SCHEMBL8581428 | 0.85 | CYP2C19 (0.35) | ALDH1A1TSHRKDM4EHPGDMAPT | |
| SCHEMBL8581699 | 0.85 | MMP13 (0.36) | ALDH1A1TSHRKDM4EHPGDMAPT | |
| SCHEMBL8584370 | 0.84 | KDM4E (0.35) | ALDH1A1TSHRKDM4EHPGDMAPT | |
| SCHEMBL8579193 | 0.83 | KDM4E (0.36) | ALDH1A1TSHRKDM4EHPGDMAPT | |
| SCHEMBL8580825 | 0.83 | MMP13 (0.34) | ALDH1A1TSHRKDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |