Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.46 |
| ▸ | CA1 | P00915 | 9/20 | 0.46 |
| ▸ | CA9 | Q16790 | 7/20 | 0.46 |
| ▸ | CA5A | P35218 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 4/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.37 |
| ▸ | CA4 | P22748 | 3/20 | 0.37 |
| ▸ | CA6 | P23280 | 3/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.37 |
| ▸ | CA3 | P07451 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583564 | 0.86 | CA2 (0.46) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL8579485 | 0.86 | CA2 (0.50) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL8609654 | 0.82 | CA2 (0.42) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL8611614 | 0.81 | CA2 (0.50) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL8578946 | 0.80 | CA2 (0.50) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL8578828 | 0.80 | SLC9A1 (0.45) | LMNAHSD17B10 | |
| SCHEMBL8534260 | 0.79 | SLC9A1 (0.54) | — | |
| SCHEMBL8580018 | 0.77 | CA2 (0.53) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL8581893 | 0.77 | CA2 (0.47) | CA2CA1CA9CA5ACA12 | |
| SCHEMBL8583374 | 0.76 | CA1 (0.55) | CA2CA1CA9CA5ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |