Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 6/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10923208 | 0.83 | BCAT2 (0.48) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL45719 | 0.81 | PARP1 (0.51) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL8576862 | 0.81 | KDM4E (0.46) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL29392318 | 0.80 | CYP17A1 (0.51) | MAPTTSHRGAAPARP1PLK4 | |
| SCHEMBL27892889 | 0.80 | AURKA (0.46) | KDM4EALDH1A1HPGDHSD17B10PARP1 | |
| SCHEMBL27913154 | 0.80 | MAPK8 (0.43) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL27895663 | 0.80 | RPS6KB1 (0.46) | KDM4EALDH1A1PARP1AURKANPC1 | |
| SCHEMBL27800518 | 0.79 | SIRT1 (0.47) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL11599894 | 0.79 | PARP1 (0.41) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL72113 | 0.78 | PARP1 (0.49) | KDM4EALDH1A1MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792840-A | SUBSTITUTED GLUCOPYRANOSYL PHOSPHATES | SANKYO COMPANY, LIMITED (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0437016-B1 | Lipid A analogues having immunoactivating and anti-tumour activity | SANKYO CO (JP) | 1996-05-01 | — | — | EP | disclosed |