Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156425 | 0.89 | ALDH1A1 (0.54) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| SCHEMBL8902281 | 0.85 | ALDH1A1 (0.62) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| SCHEMBL70202 | 0.85 | ALDH1A1 (0.62) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| SCHEMBL70201 | 0.85 | ALDH1A1 (0.62) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| SCHEMBL78873 | 0.83 | ALDH1A1 (0.59) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| SCHEMBL10590831 | 0.83 | ALDH1A1 (0.59) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| SCHEMBL29556927 | 0.83 | ALDH1A1 (0.59) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| SCHEMBL20448823 | 0.83 | ALDH1A1 (0.59) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| Benzene SCHEMBL28103329 | 0.83 | ALDH1A1 (0.59) | ALDH1A1ALOX15KDM4EHPGDCA12 | |
| SCHEMBL9445555 | 0.81 | ALDH1A1 (0.56) | ALDH1A1ALOX15KDM4EHPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792840-A | SUBSTITUTED GLUCOPYRANOSYL PHOSPHATES | SANKYO COMPANY, LIMITED (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0437016-B1 | Lipid A analogues having immunoactivating and anti-tumour activity | SANKYO CO (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0437016-A2 | Lipid A analogues having immunoactivating and anti-tumour activity | Sankyo Company Limited (JP) | 1991-07-17 | — | — | EP | disclosed |