Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | YAP1 | P46937 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8579027 | 0.99 | YAP1 (0.39) | CMA1PTGER4PDK2PDK4FFAR4 | |
| SCHEMBL8581646 | 0.94 | PDK2 (0.42) | CMA1PTGER4PDK2PDK4FFAR4 | |
| SCHEMBL8585747 | 0.90 | PDK2 (0.39) | CMA1PTGER4PDK2PDK4FFAR4 | |
| SCHEMBL8581200 | 0.85 | ALOX5AP (0.37) | PDK2PDK4YAP1KDM4EALDH1A1 | |
| SCHEMBL8581857 | 0.85 | YAP1 (0.37) | PDK2PDK4YAP1KDM4EALDH1A1 | |
| SCHEMBL8583129 | 0.85 | YAP1 (0.37) | PDK2PDK4YAP1KDM4EALDH1A1 | |
| SCHEMBL8580134 | 0.84 | YAP1 (0.39) | YAP1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8582273 | 0.84 | YAP1 (0.39) | PDK2PDK4YAP1KDM4EALDH1A1 | |
| SCHEMBL8578768 | 0.84 | YAP1 (0.39) | PDK2PDK4YAP1KDM4EALDH1A1 | |
| SCHEMBL8583580 | 0.83 | KDM4E (0.37) | PDK2PDK4YAP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |