Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578768 | 0.99 | YAP1 (0.39) | YAP1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8583575 | 0.95 | PDK2 (0.39) | YAP1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8585348 | 0.90 | ALDH1A1 (0.38) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL8580491 | 0.85 | CMA1 (0.40) | YAP1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8581200 | 0.84 | ALOX5AP (0.37) | YAP1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8579027 | 0.84 | YAP1 (0.39) | YAP1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8581857 | 0.84 | YAP1 (0.37) | YAP1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8582273 | 0.83 | YAP1 (0.39) | YAP1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8580134 | 0.83 | YAP1 (0.39) | YAP1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8583191 | 0.83 | KDM4E (0.36) | YAP1KDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |