Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | S100A4 | P26447 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31119225 | 0.90 | TDP1 (0.71) | TDP1ALDH1A1L3MBTL1GPR35TSHR | |
| SCHEMBL2088309 | 0.90 | TDP1 (0.71) | TDP1ALDH1A1L3MBTL1GPR35TSHR | |
| SCHEMBL25161887 | 0.90 | TDP1 (0.55) | TDP1ALDH1A1L3MBTL1GPR35TSHR | |
| SCHEMBL31119224 | 0.90 | TDP1 (0.71) | TDP1ALDH1A1L3MBTL1GPR35TSHR | |
| SCHEMBL1755968 | 0.88 | TDP1 (0.53) | TDP1ALDH1A1L3MBTL1GPR35TSHR | |
| SCHEMBL4564308 | 0.88 | TSHR (0.60) | TDP1ALDH1A1L3MBTL1GPR35TSHR | |
| SCHEMBL4619237 | 0.86 | TDP1 (0.52) | TDP1ALDH1A1L3MBTL1GPR35TSHR | |
| SCHEMBL589644 | 0.86 | TDP1 (0.52) | TDP1ALDH1A1L3MBTL1GPR35TSHR | |
| SCHEMBL1707141 | 0.86 | TDP1 (0.52) | TDP1ALDH1A1L3MBTL1GPR35TSHR | |
| SCHEMBL688711 | 0.86 | GPR35 (0.56) | TDP1ALDH1A1L3MBTL1GPR35TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473713-A | Hydrolysis of aryl-aliphatic ethers | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-09-25 | — | — | US | claimed |
| US-20250361627-A1 | Electrochemical Alcohol Nitration Systems and Methods | YALE UNIVERSITY (US) | 2025-11-27 | — | — | US | disclosed |
| EP-4623914-A1 | USE OF 8-HYDROXYQUINOLINE DERIVATIVE | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2025-10-01 | — | — | EP | disclosed |
| CN-120035438-A | Use of 8-hydroxyquinoline derivatives | 江苏亚虹医药科技股份有限公司 | 2025-05-23 | — | — | CN | disclosed |
| US-20240246916-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVES, PREPARATION METHOD THEREFORE AND MEDICAL USE THEREOF | JIANGSU YAHONG MEDITECH CO., LTD. (CN) | 2024-07-25 | — | — | US | disclosed |
| WO-2024118476-A1 | ELECTROCHEMICAL ALCOHOL NITRATION SYSTEMS AND METHODS | YALE UNIVERSITY (US) | 2024-06-06 | — | — | WO | disclosed |
| WO-2024109684-A1 | USE OF 8-HYDROXYQUINOLINE DERIVATIVE | 江苏亚虹医药科技股份有限公司 | 2024-05-30 | — | — | WO | disclosed |
| CN-116284040-B | Nitrogen-containing heterocyclic compound and medical application thereof | 华润医药研究院（深圳）有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118059101-A | Use of 8-hydroxyquinoline derivatives | 江苏亚虹医药科技股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| EP-4349815-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2024-04-10 | — | — | EP | disclosed |
| US-7384789-B2 | Divalent metal ion sensors and binders | THE UNIVERSITY OF NORTH DAKOTA (US) | 2008-06-10 | — | — | US | disclosed |
| US-7384789-B2 | Divalent metal ion sensors and binders | THE UNIVERSITY OF NORTH DAKOTA (US) | 2008-06-10 | — | — | US | disclosed |
| WO-2007089781-A2 | DIVALENT METAL ION SENSORS AND BINDERS | UNIVERSITY OF NORTH DAKOTA (US) | 2007-08-09 | — | — | WO | disclosed |
| WO-2007089781-A2 | DIVALENT METAL ION SENSORS AND BINDERS | UNIVERSITY OF NORTH DAKOTA (US) | 2007-08-09 | — | — | WO | disclosed |
| US-20070179311-A1 | Divalent metal ion sensors and binders | THE UNIVERSITY OF NORTH DAKOTA (US) | 2007-08-02 | — | — | US | disclosed |
| US-20070179311-A1 | Divalent metal ion sensors and binders | THE UNIVERSITY OF NORTH DAKOTA (US) | 2007-08-02 | — | — | US | disclosed |
| US-20070179311-A1 | Divalent metal ion sensors and binders | THE UNIVERSITY OF NORTH DAKOTA (US) | 2007-08-02 | — | — | US | disclosed |
| US-4473713-A | Hydrolysis of aryl-aliphatic ethers | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-09-25 | — | — | US | disclosed |
| US-4126617-A | PROPHYLAXIS | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-3959289-A | PROPHYLACTICS IN ALLERGIES | THE UPJOHN COMPANY (US) | 1976-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246916-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVES, PREPARATION METHOD THEREFORE AND MEDICAL USE THEREOF | CYP3A7, UGT1A7, UGT2B7 | TDP1 1848/4885ALDH1A1 1017/4885L3MBTL1 3845/4885 |
| US-20070179311-A1 | Divalent metal ion sensors and binders | TRPV2, TRPV6, TRPM6 | TDP1 3226/4885ALDH1A1 2607/4885L3MBTL1 1786/4885 |
| US-20250361627-A1 | Electrochemical Alcohol Nitration Systems and Methods | ADH1C, NOS1, NOS2 | TDP1 544/4885ALDH1A1 187/4885L3MBTL1 2525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.