Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8576175 | 0.83 | NPC1 (0.35) | NPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL8578924 | 0.81 | NPC1 (0.35) | NPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL8678228 | 0.79 | NPC1 (0.35) | NPC1MAPTRAB9A | |
| SCHEMBL8580933 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL8580574 | 0.71 | TNK2 (0.31) | NPC1MAPTRAB9A | |
| SCHEMBL8580928 | 0.69 | TNK2 (0.31) | NPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL8580691 | 0.67 | GRM5 (0.44) | — | |
| Hydrochloric Acid SCHEMBL8582432 | 0.65 | NPC1 (0.32) | NPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL5346729 | 0.65 | PNMT (0.46) | NPC1RAB9A | |
| SCHEMBL8580931 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830958-A | Polynuclear metallocene preparation and use | PHILLIPS PETROLEUM COMPANY (US) | 1998-11-03 | — | — | US | disclosed |
| US-5705578-A | Method for making and using a supported metallocene catalyst system | PHILLIPS PETROLEUM COMPANY (US) | 1998-01-06 | — | — | US | disclosed |