⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20330002 | 0.79 | NAMPT (0.42) | — | |
| SCHEMBL20233644 | 0.77 | NAMPT (0.41) | — | |
| SCHEMBL12522543 | 0.77 | NPSR1 (0.46) | — | |
| SCHEMBL22917193 | 0.77 | MAPT (0.33) | — | |
| SCHEMBL103430 | 0.74 | — | — | |
| SCHEMBL4982425 | 0.74 | — | — | |
| SCHEMBL23664707 | 0.74 | ALDH1A1 (0.44) | — | |
| SCHEMBL20231530 | 0.74 | TSHR (0.40) | — | |
| SCHEMBL24236652 | 0.74 | — | — | |
| SCHEMBL10878856 | 0.74 | HPGD (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998027051-A9 | CATALYTIC ASYMMETRIC AMIDOHYDROXYLATION OF OLEFINS WITH N-HALO CARBOXAMIDES | — | 1998-11-12 | — | — | WO | claimed |
| WO-1998027051-A2 | CATALYTIC ASYMMETRIC AMIDOHYDROXYLATION OF OLEFINS WITH N-HALO CARBOXAMIDES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-06-25 | — | — | WO | claimed |
| WO-2023115149-A1 | BIFUNCTIONAL SULPHONAMIDE COMPOUNDS | Anaxis Pharma Pty Ltd (AU) | 2023-06-29 | — | — | WO | disclosed |
| WO-1998027051-A9 | CATALYTIC ASYMMETRIC AMIDOHYDROXYLATION OF OLEFINS WITH N-HALO CARBOXAMIDES | — | 1998-11-12 | — | — | WO | disclosed |
| WO-1998027051-A2 | CATALYTIC ASYMMETRIC AMIDOHYDROXYLATION OF OLEFINS WITH N-HALO CARBOXAMIDES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-06-25 | — | — | WO | disclosed |