Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.61 |
| ▸ | RARG | P13631 | 10/20 | 0.61 |
| ▸ | RARA | P10276 | 6/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.61 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.61 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.61 |
| ▸ | RXRA | P19793 | 10/20 | 0.46 |
| ▸ | RXRB | P28702 | 8/20 | 0.46 |
| ▸ | RXRG | P48443 | 6/20 | 0.46 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686334 | 0.84 | RARB (0.57) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL9086322 | 0.83 | RARB (0.43) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL9765059 | 0.83 | RARB (0.57) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL8681625 | 0.82 | RARB (0.55) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL8683608 | 0.81 | RXRA (0.50) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL20587536 | 0.78 | RARB (0.77) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL31046815 | 0.78 | RARB (0.77) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL8681659 | 0.78 | RXRA (0.52) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL3302926 | 0.76 | RARB (1.00) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL7882967 | 0.76 | RARB (0.68) | RARBRARGRARACYP3A4CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798372-A | ADMINISTERING THE RETENOIDS PRIOR, DURING OR AFTER ANGIOPLASTY | ALLERGAN (US) | 1998-08-25 | — | — | US | disclosed |