Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 17/20 | 0.57 |
| ▸ | RARG | P13631 | 17/20 | 0.57 |
| ▸ | RARA | P10276 | 16/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.43 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499335 | 0.87 | RARA (0.57) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL8580707 | 0.83 | RARB (0.61) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL9817648 | 0.80 | CYP3A4 (0.76) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL444860 | 0.80 | RARB (0.78) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL9817871 | 0.79 | RARA (0.71) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL19034088 | 0.78 | RARB (0.62) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL9086322 | 0.77 | RARB (0.43) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL27304274 | 0.77 | RARB (0.62) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL7566663 | 0.76 | RARB (0.55) | RARBRARGRARACYP3A4CYP26A1 | |
| SCHEMBL16913398 | 0.76 | RARB (0.56) | RARBRARGRARACYP3A4CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5053523-A | Chemical intermediate for compounds having retinoic acid-like activity | ALLERGAN, INC. (US) | 1991-10-01 | — | — | US | disclosed |