Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.43 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27577975 | 1.00 | MEN1 (0.62) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL28544676 | 0.95 | MAPT (0.56) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL28054454 | 0.92 | TSHR (0.56) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL8580594 | 0.89 | MEN1 (0.62) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL28111504 | 0.88 | MEN1 (0.48) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL27244455 | 0.88 | MEN1 (0.48) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL8576719 | 0.86 | MAPT (0.47) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL22500203 | 0.83 | CNR2 (0.51) | KMT2AMAPTLMNAUSP2CNR2 | |
| SCHEMBL5144695 | 0.82 | MEN1 (0.69) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL5857514 | 0.82 | TSHR (0.38) | MEN1KMT2ATHRBHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753707-A | TREATING SKIN DISORDER, DERMATITIS, ROUGH SKIN; BARRIER FUNCTION | KAO CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |