Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27244455 | 1.00 | MEN1 (0.48) | MEN1KMT2AMAPTTHRBHTT | |
| SCHEMBL22500203 | 0.94 | CNR2 (0.51) | KMT2AMAPTLMNAHSD17B10CNR2 | |
| SCHEMBL8580594 | 0.92 | MEN1 (0.62) | MEN1KMT2AMAPTTHRBHTT | |
| SCHEMBL391950 | 0.91 | — | — | |
| SCHEMBL27577975 | 0.88 | MEN1 (0.62) | MEN1KMT2AMAPTTHRBHTT | |
| SCHEMBL8580710 | 0.88 | MEN1 (0.62) | MEN1KMT2AMAPTTHRBHTT | |
| SCHEMBL8575768 | 0.88 | LMNA (0.52) | MEN1KMT2AMAPTTHRBHTT | |
| SCHEMBL980183 | 0.84 | TSHR (0.44) | MAPTTHRBLMNATSHRHSD17B10 | |
| SCHEMBL199912 | 0.84 | TSHR (0.44) | MAPTTHRBLMNATSHRHSD17B10 | |
| SCHEMBL198576 | 0.84 | TSHR (0.44) | MAPTTHRBLMNATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110267949-A | SGC stimulant | 塞科里昂医疗股份有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-109790167-A | SGC stimulators | 艾恩伍德医药品股份有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-107266433-A | sGC stimulators | 铁木医药有限公司 | 2017-10-20 | — | — | CN | disclosed |
| CN-107021951-A | SGC stimulators | 铁木医药有限公司 | 2017-08-08 | — | — | CN | disclosed |
| CN-103402515-B | sGC stimulators | 铁木医药有限公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-103313976-B | sGC stimulators | 铁木医药有限公司 | 2016-11-23 | — | — | CN | disclosed |