Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 5/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30579791 | 0.71 | GHSR (0.36) | CTSKCTSS | |
| SCHEMBL29813564 | 0.71 | SYK (0.60) | SYKCYP1A2CTSKPSMB5CTSB | |
| SCHEMBL30407619 | 0.71 | SYK (0.60) | SYKCYP1A2CTSKPSMB5CTSB | |
| SCHEMBL29233251 | 0.71 | SYK (0.60) | SYKCYP1A2CTSKPSMB5CTSB | |
| SCHEMBL17616879 | 0.71 | SYK (0.60) | SYKCYP1A2CTSKPSMB5CTSB | |
| SCHEMBL17616957 | 0.71 | SYK (0.60) | SYKCYP1A2CTSKPSMB5CTSB | |
| SCHEMBL30387033 | 0.70 | SYK (0.63) | SYKCYP1A2CTSKCTSBCTSL | |
| SCHEMBL8582291 | 0.69 | SYK (0.42) | SYKCYP1A2CTSKPSMB5NTSR1 | |
| SCHEMBL8582293 | 0.69 | SYK (0.44) | SYKCYP1A2CTSKPSMB5CTSB | |
| SCHEMBL31027104 | 0.69 | SYK (0.57) | SYKCTSKCTSBATMCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837807-A | DIPEPTIDES AND CYCLIC PEPTIDE DERIVATIVES OF AMINO TETRAHYDRONAPHTHALENECARBOXYLIC ACID AND HELICAL DOMAINS | HOFFMANN-LA ROCHE INC. (US) | 1998-11-17 | — | — | US | disclosed |