Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.37 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | APC | P25054 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583068 | 0.89 | GHSR (0.43) | SYKGHSRCTSKCYP1A2PSMB5 | |
| SCHEMBL8580708 | 0.88 | GHSR (0.43) | GHSRALDH1A1HPGDHSD17B10 | |
| SCHEMBL8613091 | 0.81 | GHSR (0.40) | SYKGHSRCTSKPSMB5MAPT | |
| SCHEMBL8582293 | 0.76 | SYK (0.44) | SYKGHSRTPSAB1PLGPRSS1 | |
| SCHEMBL8581093 | 0.73 | GHSR (0.40) | SYKGHSRMAPT | |
| SCHEMBL8581721 | 0.72 | GHSR (0.48) | GHSRLMNAMAPT | |
| SCHEMBL8997593 | 0.71 | ALDH1A1 (0.35) | SYKCYP1A2PSMB5LMNAMAPT | |
| SCHEMBL8997612 | 0.70 | SYK (0.41) | SYKTPSAB1PLGPRSS1CTSK | |
| SCHEMBL30387033 | 0.70 | SYK (0.63) | SYKTPSAB1PLGPRSS1CTSK | |
| SCHEMBL8580711 | 0.69 | SYK (0.42) | SYKCTSKCYP1A2PSMB5NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837807-A | DIPEPTIDES AND CYCLIC PEPTIDE DERIVATIVES OF AMINO TETRAHYDRONAPHTHALENECARBOXYLIC ACID AND HELICAL DOMAINS | HOFFMANN-LA ROCHE INC. (US) | 1998-11-17 | — | — | US | disclosed |