Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.80 |
| ▸ | NPC1 | O15118 | 3/20 | 0.80 |
| ▸ | RAB9A | P51151 | 3/20 | 0.80 |
| ▸ | GAA | P10253 | 2/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.80 |
| ▸ | MAPT | P10636 | 2/20 | 0.80 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.80 |
| ▸ | GLA | P06280 | 1/20 | 0.80 |
| ▸ | CASP3 | P42574 | 1/20 | 0.80 |
| ▸ | RECQL | P46063 | 1/20 | 0.80 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.80 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.80 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.80 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578786 | 0.88 | KDM4E (0.61) | KDM4EALDH1A1NPC1RAB9AGAA | |
| SCHEMBL8578255 | 0.86 | ALDH1A1 (0.58) | KDM4EALDH1A1NPC1RAB9AGAA | |
| SCHEMBL8607073 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1NPC1RAB9AGAA | |
| SCHEMBL8580027 | 0.77 | KDM4E (0.48) | KDM4EALDH1A1NPC1RAB9AGAA | |
| SCHEMBL8580696 | 0.77 | ALDH1A1 (0.48) | KDM4EALDH1A1NPC1RAB9AGAA | |
| SCHEMBL8606784 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1NPC1RAB9AGAA | |
| SCHEMBL8581413 | 0.75 | ALDH1A1 (0.45) | KDM4EALDH1A1NPC1RAB9AGAA | |
| SCHEMBL8122081 | 0.72 | ALDH1A1 (0.42) | KDM4EALDH1A1NPC1RAB9AGAA | |
| SCHEMBL8123737 | 0.72 | ALDH1A1 (0.42) | KDM4EALDH1A1NPC1RAB9AGAA | |
| SCHEMBL8578246 | 0.70 | MAPT (0.40) | KDM4EALDH1A1NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998009969-A1 | NOVEL ARYL-PYRIDAZINES | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-03-12 | — | — | WO | disclosed |