Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8607232 | 0.89 | GABRP (0.46) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL10365811 | 0.88 | MAPT (0.41) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL10366098 | 0.86 | ALDH1A1 (0.43) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL7287680 | 0.86 | ALDH1A1 (0.43) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL8124757 | 0.85 | ALDH1A1 (0.39) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL10367579 | 0.85 | PRKCZ (0.41) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL8124342 | 0.85 | ALDH1A1 (0.39) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL10367467 | 0.85 | MAPT (0.44) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL10365659 | 0.84 | GRM5 (0.38) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL10368105 | 0.82 | MAPT (0.41) | ALDH1A1KDM4ENPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998009969-A1 | NOVEL ARYL-PYRIDAZINES | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-03-12 | — | — | WO | disclosed |