Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8578480 | 0.91 | CHRM2 (0.36) | SMN1; SMN2GAAALOX12L3MBTL1POLB | |
| SCHEMBL8580728 | 0.89 | SMN1; SMN2 (0.34) | SMN1; SMN2GAAALOX12L3MBTL1POLB | |
| SCHEMBL8577169 | 0.89 | SMN1; SMN2 (0.34) | SMN1; SMN2GAAALOX12L3MBTL1POLB | |
| SCHEMBL8579029 | 0.89 | SMN1; SMN2 (0.34) | SMN1; SMN2GAAALOX12L3MBTL1POLB | |
| SCHEMBL8578003 | 0.85 | MEN1 (0.32) | SMN1; SMN2GAAL3MBTL1POLBMEN1 | |
| SCHEMBL13548003 | 0.85 | TSHR (0.34) | SMN1; SMN2GRM1 | |
| SCHEMBL8575823 | 0.83 | KMT2A (0.40) | SMN1; SMN2GAAL3MBTL1MEN1HTT | |
| SCHEMBL13547993 | 0.82 | GRM1 (0.33) | SMN1; SMN2GAAGRM1OPRM1 | |
| SCHEMBL8578448 | 0.82 | SMN1; SMN2 (0.34) | SMN1; SMN2GAAALOX12L3MBTL1POLB | |
| SCHEMBL8578542 | 0.81 | OPRM1 (0.33) | SMN1; SMN2GAAMEN1KMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719310-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-02-17 | — | — | US | disclosed |
| US-5610122-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | disclosed |