Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580757 | 0.89 | SMN1; SMN2 (0.35) | SMN1; SMN2GAAALOX12P2RX7L3MBTL1 | |
| SCHEMBL8578480 | 0.89 | CHRM2 (0.36) | SMN1; SMN2GAAALOX12P2RX7L3MBTL1 | |
| SCHEMBL8578647 | 0.86 | MEN1 (0.31) | GAAL3MBTL1OPRM1POLBALDH1A1 | |
| SCHEMBL8579029 | 0.86 | SMN1; SMN2 (0.34) | SMN1; SMN2GAAALOX12P2RX7L3MBTL1 | |
| SCHEMBL8579607 | 0.84 | ALDH1A1 (0.41) | GAAP2RX7L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8579839 | 0.82 | OPRM1 (0.32) | SMN1; SMN2GAAOPRM1POLBALDH1A1 | |
| SCHEMBL8578448 | 0.80 | SMN1; SMN2 (0.34) | SMN1; SMN2GAAALOX12P2RX7L3MBTL1 | |
| SCHEMBL8577169 | 0.80 | SMN1; SMN2 (0.34) | SMN1; SMN2GAAALOX12P2RX7L3MBTL1 | |
| SCHEMBL8580890 | 0.78 | MAPK1 (0.38) | SMN1; SMN2GAAL3MBTL1POLBALDH1A1 | |
| SCHEMBL8578652 | 0.78 | CNR2 (0.32) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719310-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-02-17 | — | — | US | disclosed |
| US-5610122-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | disclosed |