Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | AGER | Q15109 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582274 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1MAPTALOX15CYP3A4 | |
| SCHEMBL8645671 | 0.83 | DPP9 (0.42) | GSRDPP8DPP9DPP7MMP2 | |
| SCHEMBL8645667 | 0.83 | DPP9 (0.42) | GSRDPP8DPP9DPP7MMP2 | |
| Lysine SCHEMBL28641263 | 0.76 | LMNA (0.59) | KDM4EALDH1A1MAPTALOX15CYP3A4 | |
| SCHEMBL9315974 | 0.76 | GSR (0.48) | GSRDPP8DPP9DPP7MMP2 | |
| SCHEMBL9315967 | 0.76 | GSR (0.48) | GSRDPP8DPP9DPP7MMP2 | |
| SCHEMBL27475290 | 0.74 | GSK3B (0.50) | ALDH1A1L3MBTL1GSRDPP8DPP9 | |
| SCHEMBL31411149 | 0.74 | GSK3B (0.50) | ALDH1A1L3MBTL1GSRDPP8DPP9 | |
| SCHEMBL29387120 | 0.73 | AKR1C3 (0.46) | MAPTGSRDPP8DPP9DPP7 | |
| Lysine SCHEMBL5907916 | 0.72 | GSR (0.57) | GSRKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296468-A | Antagonists of gonadotropin-releasing hormone; a decapeptide including an unnatural amino acid having a 3,5-diamino-1,2,4-triazole or a cyanoguanidine group; inhibits or promotes secretion of steroidal hormones; controls ovulation | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1994-03-22 | — | — | US | claimed |
| US-5744450-A | DECAPEPTIDE HORMONE INHIBITOR | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1998-04-28 | — | — | US | disclosed |
| US-5710249-A | Amino acids and processes for making peptides using same | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1998-01-20 | — | — | US | disclosed |
| US-5580957-A | GONADOTROPIN INHIBITOR | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1996-12-03 | — | — | US | disclosed |
| US-5565574-A | BIOSYNTHESIS OF SYNTHETIC PEPTIDES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1996-10-15 | — | — | US | disclosed |
| US-5352796-A | Chemical intermediates for gonadotropin-releasing hormone | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1994-10-04 | — | — | US | disclosed |
| US-5296468-A | Antagonists of gonadotropin-releasing hormone; a decapeptide including an unnatural amino acid having a 3,5-diamino-1,2,4-triazole or a cyanoguanidine group; inhibits or promotes secretion of steroidal hormones; controls ovulation | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1994-03-22 | — | — | US | disclosed |