Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315974 | 1.00 | GSR (0.48) | GSRDPP7DPP9DPP8MMP2 | |
| SCHEMBL27475290 | 0.81 | GSK3B (0.50) | GSRDPP7DPP9DPP8MMP2 | |
| SCHEMBL31411149 | 0.81 | GSK3B (0.50) | GSRDPP7DPP9DPP8MMP2 | |
| SCHEMBL8645671 | 0.79 | DPP9 (0.42) | GSRDPP7DPP9DPP8MMP2 | |
| SCHEMBL8645667 | 0.79 | DPP9 (0.42) | GSRDPP7DPP9DPP8MMP2 | |
| SCHEMBL8582274 | 0.76 | KDM4E (0.51) | GSRDPP7DPP9DPP8MMP2 | |
| SCHEMBL8580792 | 0.76 | KDM4E (0.51) | GSRDPP7DPP9DPP8MMP2 | |
| SCHEMBL28560114 | 0.75 | P2RX7 (0.38) | DPP7P2RX7 | |
| SCHEMBL15941448 | 0.75 | P2RX7 (0.38) | DPP7P2RX7 | |
| SCHEMBL28044670 | 0.74 | GSR (0.43) | GSRDPP7DPP9DPP8MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328913-A | Skin disorders and fibrotic disorders | DUKE UNIVERSITY (US) | 1994-07-12 | — | — | US | disclosed |