Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580621 | 0.95 | SKP2 (0.41) | THRATHRBMAPTCYP3A4ALDH1A1 | |
| SCHEMBL8582003 | 0.89 | MAPT (0.43) | THRATHRBMAPTCYP3A4ALDH1A1 | |
| SCHEMBL8578501 | 0.84 | SKP2 (0.45) | CA1CA2CA9HTR2AMAPT | |
| SCHEMBL8581494 | 0.83 | MAPT (0.46) | THRATHRBMAPTCYP3A4ALDH1A1 | |
| SCHEMBL8468719 | 0.79 | HTR2A (0.58) | THRATHRBCA2HTR2AMAPT | |
| SCHEMBL8153213 | 0.79 | MAPT (0.48) | THRATHRBMAPTCYP3A4ALDH1A1 | |
| SCHEMBL8579599 | 0.79 | SKP2 (0.50) | MAPTCYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL3142103 | 0.79 | THRB (0.44) | THRATHRBMAPTALDH1A1 | |
| SCHEMBL8504735 | 0.78 | HTR2A (0.61) | THRATHRBHTR2AMAPTPTGS2 | |
| SCHEMBL8468968 | 0.78 | HTR2A (0.61) | THRATHRBHTR2AMAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744203-A | POLYMER MIXTURES OF POLYURETHANES, POLYESTERS, POLYIMIDES, POLYCARBONATES AND POLYUREAS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-28 | — | — | US | disclosed |
| US-5670084-A | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |