SCHEMBL8582003

SCHEMBL8582003

CCCc1cc(Br)c(Oc2ccc(N)cc2)c(Br)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.43
ALDH1A1 P00352 5/20 0.41
TDP1 Q9NUW8 3/20 0.41
TSHR P16473 2/20 0.41
CYP3A4 P08684 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
THRA P10827 4/20 0.40
THRB P10828 4/20 0.40
RAB9A P51151 3/20 0.40
CYP19A1 P11511 2/20 0.40
NPC1 O15118 2/20 0.39
TEAD4 Q15561 1/20 0.39
PKM P14618 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
POLB P06746 1/20 0.38
MITF O75030 1/20 0.38
GAA P10253 1/20 0.38
GFER P55789 1/20 0.38
NLRP1 Q9C000 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8580621 0.91 SKP2 (0.41) MAPTALDH1A1TDP1TSHRCYP3A4
SCHEMBL8580942 0.89 THRA (0.41) MAPTALDH1A1CYP3A4SMN1; SMN2THRA
SCHEMBL8581494 0.87 MAPT (0.46) MAPTALDH1A1TDP1TSHRCYP3A4
SCHEMBL8153213 0.83 MAPT (0.48) MAPTALDH1A1TDP1TSHRCYP3A4
SCHEMBL8578456 0.82 ALDH1A1 (0.46) MAPTALDH1A1TDP1TSHRCYP3A4
SCHEMBL8578368 0.81 CYP19A1 (0.44) MAPTALDH1A1TDP1TSHRCYP3A4
SCHEMBL8576892 0.81 ALDH1A1 (0.47) MAPTALDH1A1TDP1TSHRCYP3A4
SCHEMBL8579669 0.79 CYP19A1 (0.59) TDP1SMN1; SMN2CYP19A1
SCHEMBL5073534 0.79 THRA (0.60) THRATHRBPOLB
SCHEMBL3131477 0.79 THRB (0.48) MAPTALDH1A1THRATHRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110408024-B Polyimide precursor composition, polyamic acid, polyimide resin, polyimide film, and optical device 东京应化工业株式会社 2023-11-17 CN disclosed
US-5744203-A POLYMER MIXTURES OF POLYURETHANES, POLYESTERS, POLYIMIDES, POLYCARBONATES AND POLYUREAS HOECHST AKTIENGESELLSCHAFT (DE) 1998-04-28 US disclosed
US-5670084-A Alignment layer material for liquid crystal display devices HOECHST AKTIENGESELLSCHAFT (DE) 1997-09-23 US disclosed