Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 4/20 | 0.31 |
| ▸ | FPR2 | P25090 | 4/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5834908 | 0.81 | GHSR (0.47) | GHSRKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8569151 | 0.80 | GHSR (0.32) | GHSRAAK1KMT2ANPC1RAB9A | |
| SCHEMBL1162409 | 0.80 | GHSR (0.48) | GHSRACHEBACE1CA1CA2 | |
| SCHEMBL8581652 | 0.80 | GHSR (0.48) | GHSRACHEBACE1CA1CA2 | |
| SCHEMBL1162415 | 0.80 | GHSR (0.48) | GHSRACHEBACE1CA1CA2 | |
| SCHEMBL8844917 | 0.76 | GHSR (0.35) | GHSRAAK1KMT2ANPC1RAB9A | |
| SCHEMBL31214681 | 0.73 | GHSR (0.41) | GHSRKMT2AMEN1CA1CA2 | |
| SCHEMBL2813574 | 0.73 | GHSR (0.63) | GHSRBACE1CA12CA1CA7 | |
| SCHEMBL18614234 | 0.73 | GHSR (0.63) | GHSRBACE1CA12CA1CA7 | |
| SCHEMBL29715495 | 0.73 | GHSR (0.63) | GHSRBACE1CA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837807-A | DIPEPTIDES AND CYCLIC PEPTIDE DERIVATIVES OF AMINO TETRAHYDRONAPHTHALENECARBOXYLIC ACID AND HELICAL DOMAINS | HOFFMANN-LA ROCHE INC. (US) | 1998-11-17 | — | — | US | disclosed |
| US-5644024-A | MIMICS OF PEPTIDE DOMAINS, SEQUENCE DETERMINATION, DRUGS | HOFFMANN-LA ROCHE INC. (US) | 1997-07-01 | — | — | US | disclosed |