Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | MTTP | P55157 | 2/20 | 0.31 |
| ▸ | TACR3 | P29371 | 6/20 | 0.30 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.30 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | TACR2 | P21452 | 3/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL824992 | 0.88 | KCNH2 (0.48) | KCNH2OPRK1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL828601 | 0.80 | KCNH2 (0.37) | KCNH2CYP3A4CYP1A2MTTPTACR3 | |
| SCHEMBL827540 | 0.74 | KLRK1 (0.36) | KCNH2MTTPTACR3 | |
| SCHEMBL825058 | 0.73 | CYP3A4 (0.48) | KCNH2OPRK1CYP3A4CYP2C9CYP1A2 | |
| SCHEMBL3060734 | 0.72 | CYP3A4 (0.45) | KCNH2OPRK1CYP3A4CYP2C9CYP1A2 | |
| SCHEMBL827539 | 0.72 | KCNH2 (0.32) | KCNH2OPRK1TACR3NPSR1 | |
| SCHEMBL883039 | 0.70 | KCNH2 (0.58) | KCNH2OPRK1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL828862 | 0.69 | CYP3A4 (0.41) | KCNH2OPRK1CYP3A4CYP2C9CYP1A2 | |
| SCHEMBL10177442 | 0.69 | KCNH2 (0.56) | KCNH2OPRK1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16282928 | 0.69 | KCNH2 (0.47) | KCNH2OPRK1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143301-B2 | Hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |
| US-20100260708-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100260708-A1 | Hepatitis C Virus Inhibitors | HAVCR2, PYGL, HCCS | KCNH2 4523/4885OPRK1 1789/4885CYP3A4 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.