Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 3/20 | 0.41 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.41 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 4/20 | 0.39 |
| ▸ | PYGL | P06737 | 6/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287585 | 0.81 | TSHR (0.49) | PYGLEGFR | |
| SCHEMBL11287590 | 0.81 | TSHR (0.49) | PYGLEGFR | |
| SCHEMBL11291868 | 0.81 | TSHR (0.49) | PYGLEGFR | |
| SCHEMBL15018216 | 0.79 | KDM1A (0.41) | SIGMAR1KDM1A | |
| SCHEMBL15036590 | 0.79 | KDM1A (0.41) | SIGMAR1KDM1A | |
| SCHEMBL18766100 | 0.79 | KDM1A (0.43) | SIGMAR1KDM1A | |
| SCHEMBL15036547 | 0.79 | KDM1A (0.43) | SIGMAR1KDM1A | |
| SCHEMBL20720128 | 0.79 | KDM1A (0.43) | SIGMAR1KDM1A | |
| SCHEMBL8296922 | 0.78 | PYGL (0.41) | PYGL | |
| SCHEMBL7736693 | 0.77 | GRM2 (0.37) | SIGMAR1PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673288-A1 | PEPTIDE FOR USE IN THE TREATMENT OF SKIN CONDITIONS | Organo Balance GmbH (DE) | 2013-12-18 | — | — | EP | claimed |
| WO-2012107244-A1 | PEPTIDE FOR USE IN THE TREATMENT OF SKIN CONDITIONS | ORGANOBALANCE GMBH (DE) | 2012-08-16 | — | — | WO | claimed |
| US-5801274-A | N- mercaptoacyl(amino acid or peptide)! compounds and S-lipophilic aliphatic carbonyl derivatives thereof as antihypertensives | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-09-01 | — | — | US | disclosed |
| US-5591891-A | PEPTIDASE INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-01-07 | — | — | US | disclosed |
| WO-1994017036-A1 | S-LIPOPHILIC ALIPHATIC CARBONYL [N-MERCAPTOACYL-(AMINO ACID OR PEPTIDE)] COMPOUNDS AS ANTIHYPERTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1994-08-04 | — | — | WO | disclosed |