Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580151 | 1.00 | LMNA (0.37) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL3687107 | 0.83 | PDE4A (0.47) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL536485 | 0.83 | PDE4A (0.47) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL526989 | 0.81 | PDE4A (0.39) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL10699708 | 0.80 | USP2 (0.50) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| Mannitol SCHEMBL28986333 | 0.78 | LMNA (0.55) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL459979 | 0.76 | LMNA (0.39) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL5689712 | 0.74 | KDM4E (0.32) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| Demannose SCHEMBL4340605 | 0.74 | PDE4A (0.39) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL4314209 | 0.73 | PDE4A (0.36) | LMNAL3MBTL1PDE4ATDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025940-A1 | INHIBITORS OF GLYCOSYLTRANSFERASES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-06-18 | — | — | WO | claimed |
| WO-1998025940-A1 | INHIBITORS OF GLYCOSYLTRANSFERASES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-06-18 | — | — | WO | disclosed |