SCHEMBL536485

SCHEMBL536485

O=C([C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)P(=O)(O)OP(=O)(O)O

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.47
LMNA P02545 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
USP2 O75604 1/20 0.36
SLCO1B1 Q9Y6L6 1/20 0.36
PGD P52209 3/20 0.34
FDPS P14324 1/20 0.31
BLM P54132 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3687107 1.00 PDE4A (0.47) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL526989 0.95 PDE4A (0.39) PDE4ALMNAL3MBTL1TDP1USP2
Demannose SCHEMBL4340605 0.89 PDE4A (0.39) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL4314209 0.86 PDE4A (0.36) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL8580151 0.83 LMNA (0.37) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL10699708 0.83 USP2 (0.50) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL8582227 0.83 LMNA (0.37) PDE4ALMNAL3MBTL1TDP1USP2
Mannitol SCHEMBL28986333 0.80 LMNA (0.55) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL360335 0.79 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL6282106 0.79 PDE4A (0.56) PDE4ALMNAL3MBTL1TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0635051-B1 INCREASING THE TREHALOSE CONTENT OF ORGANISMS BY TRANSFORMING THEM WITH COMBINATIONS OF THE STRUCTURAL GENES FOR TREHALOSE SYNTHASE BTG INT LTD (GB) 2004-06-23 EP claimed
EP-0763132-B1 ASSAY FOR ENZYME ACTIVITY USING A MICROFLUOROMETRIC ASSAY ISOLAB INC (US) 2001-01-24 EP claimed
WO-2026102337-A1 ENPP1 FOR USE IN THE TREATMENT OF CALCIPHYLAXIS BIOMARIN PHARMACEUTICAL INC. (US) 2026-05-15 WO disclosed
US-20260049294-A1 ENPP1 Polypeptides and Methods of Using Same UNIV YALE (US) 2026-02-19 US disclosed
US-20260041742-A1 METHOD AND COMPOSITIONS FOR TREATMENT, AMELIORATION, AND/OR PREVENTION OF DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS (DISH) UNIV YALE (US) 2026-02-12 US disclosed
US-20260015595-A1 ENGINEERED GLYCOSYLTRANSFERASES AND STEVIOL GLYCOSIDE GLUCOSYLATION METHODS TATE & LYLE SOLUTIONS USA LLC (US) 2026-01-15 US disclosed
US-20260002136-A1 ENGINEERED GLYCOSYLTRANSFERASES AND STEVIOL GLYCOSIDE GLUCOSYLATION METHODS TATE & LYLE SOLUTIONS USA LLC (US) 2026-01-01 US disclosed
US-20250388882-A1 COMPOSITIONS FOR TREATING ECTOPIC CALCIFICATION DISORDERS, AND METHODS USING SAME UNIV YALE (US) 2025-12-25 US disclosed
US-12454682-B2 Engineered glycosyltransferases and steviol glycoside glucosylation methods TATE & LYLE SOLUTIONS USA LLC (US) 2025-10-28 US disclosed
WO-2025042995-A9 TREATMENT OF ENPP1 DEFICIENCY AND ABCC6 DEFICIENCY IN CHILDREN INOZYME PHARMA, INC. (US) 2025-10-16 WO disclosed
US-12404499-B2 Engineered glycosyltransferases and steviol glycoside glucosylation methods TATE & LYLE SOLUTIONS USA LLC (US) 2025-09-02 US disclosed
EP-0918868-A2 ANTIMICROBIAL AGENTS, DIAGNOSTIC REAGENTS, AND VACCINES BASED ON UNIQUE APICOMPLEXAN PARASITE COMPONENTS ARCH DEVELOPMENT CORPORATION (US) 1999-06-02 EP disclosed
WO-1998003661-A2 ANTIMICROBIAL AGENTS, DIAGNOSTIC REAGENTS, AND VACCINES BASED ON UNIQUE APICOMPLEXAN PARASITE COMPONENTS ARCH DEVELOPMENT CORPORATION (US) 1998-01-29 WO disclosed
EP-0763118-A1 TRANSGENIC PLANTS PRODUCING TREHALOSE Alko Group Ltd. (FI) 1997-03-19 EP disclosed
WO-1996000789-A1 TRANSGENIC PLANTS PRODUCING TREHALOSE ALKO GROUP LIMITED (FI) 1996-01-11 WO disclosed
EP-0617625-A1 USE OF UDPG AS CANCER THERAPY RESCUE AGENT BOEHRINGER MANNHEIM ITALIA S.p.A. (IT) 1994-10-05 EP disclosed
WO-1993013779-A3 USE OF UDPG AS CANCER THERAPY RESCUE AGENT BOEHRINGER MANNHEIM ITALIA (IT) 1993-08-19 WO disclosed
WO-1993013779-A2 USE OF UDPG AS CANCER THERAPY RESCUE AGENT BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1993-07-22 WO disclosed
WO-1991000867-A1 5'-DIPHOSPHOHEXOSE NUCLEOSIDE PHARMACEUTICAL COMPOSITIONS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1991-01-24 WO disclosed
WO-1986003678-A1 COMPOSITION AND METHOD FOR TREATMENT OF TUMORS WITH UDPG MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES (US) 1986-07-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260002136-A1 ENGINEERED GLYCOSYLTRANSFERASES AND STEVIOL GLYCOSIDE GLUCOSYLATION METHODS UGGT1, UGCG, COASY PDE4A 963/4885LMNA 3600/4885L3MBTL1 892/4885
US-20250388882-A1 COMPOSITIONS FOR TREATING ECTOPIC CALCIFICATION DISORDERS, AND METHODS USING SAME ALPI, ENPP3, ALPP PDE4A 620/4885LMNA 4175/4885L3MBTL1 3794/4885
US-20260015595-A1 ENGINEERED GLYCOSYLTRANSFERASES AND STEVIOL GLYCOSIDE GLUCOSYLATION METHODS UGGT1, COASY, GBA3 PDE4A 2095/4885LMNA 4011/4885L3MBTL1 1337/4885
US-20260049294-A1 ENPP1 Polypeptides and Methods of Using Same ENPP1, ENPP3, PNP PDE4A 249/4885LMNA 1872/4885L3MBTL1 235/4885
US-12454682-B2 Engineered glycosyltransferases and steviol glycoside glucosylation methods UGGT1, GBA3, UGCG PDE4A 2170/4885LMNA 4401/4885L3MBTL1 2716/4885
US-20260041742-A1 METHOD AND COMPOSITIONS FOR TREATMENT, AMELIORATION, AND/OR PREVENTION OF DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS (DISH) SOST, ALB, ENPP2 PDE4A 2906/4885LMNA 3957/4885L3MBTL1 1051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.