Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 17/20 | 0.67 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545966 | 0.93 | TBXAS1 (0.78) | TBXAS1TBXA2RPTGDR2 | |
| SCHEMBL8537433 | 0.92 | TBXAS1 (0.76) | TBXAS1TBXA2RPTGDR2 | |
| SCHEMBL8542545 | 0.85 | TBXAS1 (0.88) | TBXAS1TBXA2RPTGDR2 | |
| SCHEMBL8538888 | 0.83 | TBXAS1 (0.75) | TBXAS1TBXA2RPTGDR2 | |
| SCHEMBL8539545 | 0.82 | TBXAS1 (0.67) | TBXAS1PTGDR2 | |
| SCHEMBL8544370 | 0.81 | TBXAS1 (0.53) | TBXAS1PTGDR2 | |
| SCHEMBL8538829 | 0.78 | TBXAS1 (0.59) | TBXAS1TBXA2RPTGDR2 | |
| SCHEMBL8583418 | 0.77 | TBXAS1 (0.57) | TBXAS1TBXA2R | |
| SCHEMBL8541550 | 0.77 | TBXAS1 (0.78) | TBXAS1 | |
| SCHEMBL8538702 | 0.77 | TBXAS1 (0.64) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744488-A | 1-CARBOXYALKYL-3-ALKYL OR PHENYL-5-ORGANOSULFONAMIDE OR -AMIDE INDOLES; ATHERSCLEROSIS; ANGINA; PREVENTING ANGIOPLASTY OCCULSION; THROMBOXANE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1998-04-28 | — | — | US | claimed |