Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541824 | 0.92 | TBXAS1 (0.67) | TBXAS1TBXA2R | |
| SCHEMBL8608385 | 0.90 | TBXAS1 (0.56) | TBXAS1TBXA2R | |
| SCHEMBL8538829 | 0.85 | TBXAS1 (0.59) | TBXAS1TBXA2R | |
| SCHEMBL8537433 | 0.85 | TBXAS1 (0.76) | TBXAS1TBXA2R | |
| SCHEMBL8543863 | 0.79 | TBXAS1 (0.46) | TBXAS1 | |
| SCHEMBL8582385 | 0.77 | TBXAS1 (0.67) | TBXAS1TBXA2R | |
| SCHEMBL8538814 | 0.77 | TBXAS1 (0.63) | TBXAS1TBXA2R | |
| SCHEMBL8542545 | 0.77 | TBXAS1 (0.88) | TBXAS1TBXA2R | |
| SCHEMBL8541115 | 0.75 | TBXAS1 (0.65) | TBXAS1 | |
| SCHEMBL8538888 | 0.75 | TBXAS1 (0.75) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744488-A | 1-CARBOXYALKYL-3-ALKYL OR PHENYL-5-ORGANOSULFONAMIDE OR -AMIDE INDOLES; ATHERSCLEROSIS; ANGINA; PREVENTING ANGIOPLASTY OCCULSION; THROMBOXANE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1998-04-28 | — | — | US | claimed |