Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580648 | 0.88 | CNR2 (0.41) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL8581357 | 0.86 | CNR2 (0.45) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL8581701 | 0.85 | CNR2 (0.44) | ALDH1A1KMT2ATSHR | |
| SCHEMBL8582511 | 0.83 | CMA1 (0.43) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL8584499 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL8582664 | 0.81 | KDM4E (0.41) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL8583684 | 0.81 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL8578774 | 0.79 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL8529003 | 0.79 | SLC9A1 (0.42) | — | |
| SCHEMBL8584161 | 0.79 | KDM4E (0.37) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |