Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15413215 | 0.85 | FOLH1 (0.36) | FOLH1HTR7CHRM1TBXA2RADRA1A | |
| SCHEMBL15413216 | 0.83 | FOLH1 (0.38) | FOLH1HTR7CHRM1TBXA2RADRA1A | |
| SCHEMBL2737085 | 0.83 | ALDH1A1 (0.38) | FOLH1HTR7CHRM1TBXA2RADRA1A | |
| SCHEMBL19615002 | 0.81 | FOLH1 (0.35) | FOLH1HTR7CHRM1TBXA2RADRA1A | |
| SCHEMBL22355998 | 0.81 | ALOX15 (0.40) | FOLH1HTR7CHRM1TBXA2RADRA1A | |
| SCHEMBL24023415 | 0.79 | FOLH1 (0.34) | FOLH1HTR7CHRM1TBXA2RADRA1A | |
| SCHEMBL21791312 | 0.79 | ELANE (0.37) | FOLH1HTR7CHRM1TBXA2RADRA1A | |
| SCHEMBL24004385 | 0.79 | FOLH1 (0.34) | FOLH1HTR7CHRM1TBXA2RADRA1A | |
| SCHEMBL10293858 | 0.79 | ELANE (0.39) | FOLH1HTR7CHRM1TBXA2RADRA1A | |
| SCHEMBL21125401 | 0.77 | FOLH1 (0.36) | FOLH1HTR7CHRM1TBXA2RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705527-A | VASODILATORS AND ANGINA PECTORIS | SANKYO COMPANY, LIMITED (JP) | 1998-01-06 | — | — | US | claimed |
| EP-0641769-B1 | AMINO ACID DERIVATIVE | SANKYO CO (JP) | 1997-01-29 | — | — | EP | claimed |
| EP-0641769-A1 | AMINO ACID DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1995-03-08 | — | — | EP | claimed |
| US-5705527-A | VASODILATORS AND ANGINA PECTORIS | SANKYO COMPANY, LIMITED (JP) | 1998-01-06 | — | — | US | disclosed |
| EP-0641769-B1 | AMINO ACID DERIVATIVE | SANKYO CO (JP) | 1997-01-29 | — | — | EP | disclosed |
| EP-0641769-A1 | AMINO ACID DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1995-03-08 | — | — | EP | disclosed |