Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581321 | 0.96 | TRPV1 (0.39) | TRPV1VCAM1ALDH1A1TDP1KMT2A | |
| SCHEMBL8581811 | 0.82 | CMA1 (0.39) | ALDH1A1CNR2KMT2AMEN1KDM4E | |
| SCHEMBL8580630 | 0.81 | SLC9A1 (0.36) | — | |
| SCHEMBL8581767 | 0.81 | CNR2 (0.38) | ALDH1A1CNR2KMT2AMEN1KDM4E | |
| SCHEMBL8581357 | 0.81 | CNR2 (0.45) | TRPV1ALDH1A1CNR2KMT2AMEN1 | |
| SCHEMBL8582692 | 0.81 | CNR2 (0.40) | ALDH1A1TDP1CNR2KMT2AMEN1 | |
| SCHEMBL8581034 | 0.81 | PPARA (0.40) | ALDH1A1TDP1CNR2KMT2AMEN1 | |
| SCHEMBL8579199 | 0.81 | CNR2 (0.38) | ALDH1A1CNR2KMT2AMEN1KDM4E | |
| SCHEMBL8582608 | 0.81 | CNR2 (0.38) | ALDH1A1CNR2KMT2AMEN1KDM4E | |
| SCHEMBL8585560 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TDP1CNR2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |