Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544076 | 0.75 | TBXAS1 (1.00) | TBXAS1PTGDR2 | |
| SCHEMBL8580490 | 0.74 | TBXAS1 (0.61) | TBXAS1PTGDR2 | |
| SCHEMBL8583166 | 0.72 | TBXAS1 (0.63) | TBXAS1PTGDR2 | |
| SCHEMBL8543306 | 0.72 | TBXAS1 (0.85) | TBXAS1PTGDR2 | |
| SCHEMBL8538416 | 0.72 | TBXAS1 (0.88) | TBXAS1PTGDR2 | |
| SCHEMBL8541550 | 0.69 | TBXAS1 (0.78) | TBXAS1 | |
| SCHEMBL9023844 | 0.66 | TBXAS1 (0.72) | TBXAS1 | |
| SCHEMBL8583787 | 0.66 | TBXAS1 (0.58) | TBXAS1PTGDR2 | |
| Dazmegrel SCHEMBL154037 | 0.64 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL1466115 | 0.63 | PTGDR2 (0.84) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744488-A | 1-CARBOXYALKYL-3-ALKYL OR PHENYL-5-ORGANOSULFONAMIDE OR -AMIDE INDOLES; ATHERSCLEROSIS; ANGINA; PREVENTING ANGIOPLASTY OCCULSION; THROMBOXANE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1998-04-28 | — | — | US | disclosed |