Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 14/20 | 0.61 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583185 | 0.82 | TBXAS1 (0.62) | TBXAS1PTGDR2 | |
| SCHEMBL8538416 | 0.76 | TBXAS1 (0.88) | TBXAS1PTGDR2 | |
| SCHEMBL8541115 | 0.75 | TBXAS1 (0.65) | TBXAS1ALDH1A1 | |
| SCHEMBL8583413 | 0.75 | TBXAS1 (0.52) | TBXAS1PTGDR2HDAC3HDAC4HDAC1 | |
| SCHEMBL8583165 | 0.74 | TBXAS1 (0.59) | TBXAS1PTGDR2 | |
| SCHEMBL8541550 | 0.73 | TBXAS1 (0.78) | TBXAS1ALDH1A1CYP19A1 | |
| SCHEMBL8543963 | 0.72 | TBXAS1 (0.58) | TBXAS1ALDH1A1CYP19A1 | |
| SCHEMBL8544076 | 0.72 | TBXAS1 (1.00) | TBXAS1PTGDR2 | |
| SCHEMBL10373940 | 0.71 | TBXAS1 (0.63) | TBXAS1PTGDR2ALDH1A1HDAC3HDAC4 | |
| SCHEMBL9814947 | 0.71 | TBXAS1 (0.56) | TBXAS1PTGDR2ALDH1A1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744488-A | 1-CARBOXYALKYL-3-ALKYL OR PHENYL-5-ORGANOSULFONAMIDE OR -AMIDE INDOLES; ATHERSCLEROSIS; ANGINA; PREVENTING ANGIOPLASTY OCCULSION; THROMBOXANE SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1998-04-28 | — | — | US | claimed |