Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 10/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10810664 | 0.82 | CYP19A1 (0.49) | CYP19A1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10901545 | 0.75 | APP (0.41) | CYP19A1MAPTTDP1APP | |
| SCHEMBL8133457 | 0.75 | ALDH1A1 (0.52) | CYP19A1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10814556 | 0.75 | MAPT (0.50) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL619318 | 0.73 | MAPT (0.52) | CHUKMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10811090 | 0.72 | MAPT (0.60) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL6973083 | 0.70 | MAPT (0.56) | CHUKMEN1KMT2AALDH1A1MAPT | |
| Iodide SCHEMBL11813329 | 0.69 | MAPT (0.55) | CHUKMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10809694 | 0.68 | ALDH1A1 (0.41) | KMT2AALDH1A1MAPTTDP1APP | |
| SCHEMBL10812979 | 0.68 | TDP1 (0.41) | MEN1KMT2AALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935969-A | Pyrido-thiopyrandoinazoles with antitumor activity | UNIVERSITY OF VERMONT (US) | 1999-08-10 | — | — | US | disclosed |