Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15967436 | 0.88 | MEN1 (0.46) | LMNAKMT2AMEN1CYP2C9CYP3A4 | |
| SCHEMBL8583251 | 0.87 | MEN1 (0.45) | LMNAKMT2AMEN1CYP2C9CYP3A4 | |
| SCHEMBL8221672 | 0.83 | LMNA (0.48) | LMNAKMT2AMEN1CYP2C9CYP3A4 | |
| SCHEMBL8581880 | 0.80 | MEN1 (0.59) | LMNAKMT2AMEN1CYP2C9CYP3A4 | |
| SCHEMBL6520376 | 0.79 | GPR132 (0.47) | LMNAHDAC1HDAC6GPR132 | |
| SCHEMBL22262958 | 0.77 | MEN1 (0.46) | LMNAKMT2AMEN1CYP2C9CYP3A4 | |
| SCHEMBL22262960 | 0.77 | MEN1 (0.46) | LMNAKMT2AMEN1CYP2C9CYP3A4 | |
| SCHEMBL6522512 | 0.76 | KMT2A (0.44) | LMNAKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL6522516 | 0.76 | KMT2A (0.44) | LMNAKMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL4028022 | 0.76 | KMT2A (0.53) | LMNAKMT2AMEN1CYP3A4ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705527-A | VASODILATORS AND ANGINA PECTORIS | SANKYO COMPANY, LIMITED (JP) | 1998-01-06 | — | — | US | disclosed |