Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581031 | 0.93 | CMA1 (0.39) | CMA1FFAR4KDM4EALDH1A1MAPT | |
| SCHEMBL8581792 | 0.90 | CMA1 (0.42) | CMA1FFAR4KDM4EALDH1A1MAPT | |
| SCHEMBL8583192 | 0.86 | CMA1 (0.40) | CMA1FFAR4KDM4EALDH1A1MAPT | |
| SCHEMBL8584370 | 0.86 | KDM4E (0.35) | CMA1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8583897 | 0.86 | KDM4E (0.36) | CMA1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8585519 | 0.86 | KDM4E (0.35) | CMA1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8582956 | 0.85 | ALDH1A1 (0.34) | CMA1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8580948 | 0.84 | KDM4E (0.34) | CMA1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8582886 | 0.84 | CMA1 (0.42) | CMA1FFAR4KDM4EALDH1A1MAPT | |
| SCHEMBL8583990 | 0.83 | KDM4E (0.35) | CMA1KDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |