Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CMA1 | P23946 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8584370 | 0.90 | KDM4E (0.35) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL8582956 | 0.89 | ALDH1A1 (0.34) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL8583897 | 0.85 | KDM4E (0.36) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL8583303 | 0.84 | CMA1 (0.41) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL8583887 | 0.83 | ALDH1A1 (0.34) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL8585519 | 0.83 | KDM4E (0.35) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL8580422 | 0.82 | ALDH1A1 (0.34) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL8581511 | 0.81 | KDM4E (0.36) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL8529843 | 0.81 | SLC9A1 (0.40) | — | |
| SCHEMBL8580855 | 0.80 | KDM4E (0.37) | KDM4EALDH1A1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |