Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | CAD | P27708 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583393 | 1.00 | GAA (0.50) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL15257970 | 0.84 | GAA (0.46) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL13624780 | 0.83 | GAA (0.50) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL25274352 | 0.82 | CAD (0.47) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL10612838 | 0.82 | GAA (0.48) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL9729395 | 0.82 | GAA (0.48) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL8583427 | 0.80 | L3MBTL1 (0.36) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL8583430 | 0.80 | L3MBTL1 (0.36) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL468760 | 0.80 | L3MBTL1 (0.50) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL3565347 | 0.80 | L3MBTL1 (0.69) | GAAMGAMSIMGAM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405987-A | N-hydroxyaspartic acid derivatives; chemical intermediates | HOECHST CELANESE CORPORATION (US) | 1995-04-11 | — | — | US | claimed |
| US-5322948-A | Reacting unsaturated diacid or derivative with hydroxylamine or a salt thereof to form N-hydroxy-2-aminobutane diacid derivative | HOECHST CELANESE CORPORATION (US) | 1994-06-21 | — | — | US | claimed |
| EP-0511446-A2 | Process for preparing pyridinecarboxylic acid derivatives | HOECHST CELANESE CORPORATION (US) | 1992-11-04 | — | — | EP | claimed |
| CN-1058205-A | The method for preparing pyridine and quinoline | HOECHST CELANESE CORP (US) | 1992-01-29 | — | — | CN | claimed |
| EP-0452094-A2 | A method of the preparation of N-hydroxy aspartic acid derivate | HOECHST CELANESE CORPORATION (US) | 1991-10-16 | — | — | EP | claimed |
| CN-1049844-A | The preparation method of pyridine carboxylic acid derivatives | HOECHST CELANESE CORP (US) | 1991-03-13 | — | — | CN | claimed |
| EP-0415767-A2 | Process for preparing pyridine carboxylic acid derivatives | HOECHST CELANESE CORPORATION (US) | 1991-03-06 | — | — | EP | claimed |
| US-5808067-A | Process for preparing pyridine and quinoline derivatives | HOECHST CELANESE CORPORATION (US) | 1998-09-15 | — | — | US | disclosed |
| US-5405987-A | N-hydroxyaspartic acid derivatives; chemical intermediates | HOECHST CELANESE CORPORATION (US) | 1995-04-11 | — | — | US | disclosed |
| US-5322948-A | Reacting unsaturated diacid or derivative with hydroxylamine or a salt thereof to form N-hydroxy-2-aminobutane diacid derivative | HOECHST CELANESE CORPORATION (US) | 1994-06-21 | — | — | US | disclosed |
| EP-0564083-A1 | Conversion of pyridine-2,3-dicarboxylic acid esters to their cyclic anhydrides | HOECHST CELANESE CORPORATION (US) | 1993-10-06 | — | — | EP | disclosed |
| US-5208342-A | Hydrolysis and dehydration | HOECHST CELANESE CORPORATION (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0511446-A2 | Process for preparing pyridinecarboxylic acid derivatives | HOECHST CELANESE CORPORATION (US) | 1992-11-04 | — | — | EP | disclosed |
| CN-1058205-A | The method for preparing pyridine and quinoline | HOECHST CELANESE CORP (US) | 1992-01-29 | — | — | CN | disclosed |
| EP-0452094-A2 | A method of the preparation of N-hydroxy aspartic acid derivate | HOECHST CELANESE CORPORATION (US) | 1991-10-16 | — | — | EP | disclosed |
| CN-1049844-A | The preparation method of pyridine carboxylic acid derivatives | HOECHST CELANESE CORP (US) | 1991-03-13 | — | — | CN | disclosed |
| EP-0415767-A2 | Process for preparing pyridine carboxylic acid derivatives | HOECHST CELANESE CORPORATION (US) | 1991-03-06 | — | — | EP | disclosed |