SCHEMBL85834

SCHEMBL85834

C=C(C)C(=O)OCCNC(=O)OCC(O)(F)F

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.40
TSHR P16473 3/20 0.39
ACHE P22303 8/20 0.34
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10902664 0.89 THRB (0.41) THRBTSHRACHEALDH1A1LMNA
SCHEMBL14330808 0.88 THRB (0.40) THRBTSHRACHEALDH1A1LMNA
SCHEMBL10205463 0.87 THRB (0.39) THRBTSHRACHEALDH1A1LMNA
SCHEMBL15292840 0.85 THRB (0.38) THRBTSHRACHEALDH1A1LMNA
SCHEMBL15242153 0.85 THRB (0.36) THRBTSHRACHE
SCHEMBL6253284 0.84 THRB (0.42) THRBTSHRACHEALDH1A1LMNA
SCHEMBL17750747 0.84 THRB (0.37) THRBTSHRACHEALDH1A1LMNA
SCHEMBL14551152 0.83 THRB (0.36) THRBTSHRACHEALDH1A1
SCHEMBL12994537 0.83 THRB (0.36) THRBTSHRACHEALDH1A1
SCHEMBL1755340 0.83 THRB (0.36) THRBTSHRACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9314548-B2 Nanostructured surfaces for biomedical/biomaterial applications and processes thereof LIQUIDIA TECHNOLOGIES, INC. (US) 2016-04-19 US disclosed
US-20150148903-A1 Nanostructured Surfaces for Biomedical/Biomaterial Applications and Processes Thereof LIQUIDIA TECHNOLOGIES, INC. (US) 2015-05-28 US disclosed
US-8535879-B2 Structuring hydrogels DWI AN DER RWTH AACHEN E.V. (DE) 2013-09-17 US disclosed
US-20120189728-A1 METHODS AND MATERIALS FOR FABRICATING LAMINATE NANOMOLDS AND NANOPARTICLES THEREFROM LIQUIDIA TECHNOLOGIES, INC. (US) 2012-07-26 US disclosed
US-8128393-B2 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. (US) 2012-03-06 US disclosed
US-20090250588-A1 Nanostructured Surfaces for Biomedical/Biomaterial Applications and Processes Thereof LIQUIDIA TECHNOLOGIES, INC. (US) 2009-10-08 US disclosed
US-20080131692-A1 Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom LIQUIDIA TECHNOLOGIES, INC. 2008-06-05 US disclosed
US-20070286883-A1 STRUCTURING HYDROGELS DWI AN DER RWTH AACHEN E.V. (DE) 2007-12-13 US disclosed