Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 8/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10902664 | 0.88 | THRB (0.41) | THRBTSHRALDH1A1ACHELMNA | |
| SCHEMBL14330808 | 0.87 | THRB (0.40) | THRBTSHRALDH1A1ACHELMNA | |
| SCHEMBL85834 | 0.87 | THRB (0.40) | THRBTSHRALDH1A1ACHELMNA | |
| SCHEMBL17750747 | 0.86 | THRB (0.37) | THRBTSHRALDH1A1ACHELMNA | |
| SCHEMBL14551152 | 0.85 | THRB (0.36) | THRBTSHRALDH1A1ACHE | |
| SCHEMBL1755340 | 0.85 | THRB (0.36) | THRBTSHRALDH1A1ACHE | |
| SCHEMBL15292840 | 0.84 | THRB (0.38) | THRBTSHRALDH1A1ACHELMNA | |
| SCHEMBL12021040 | 0.83 | THRB (0.36) | THRBTSHRACHE | |
| SCHEMBL15242153 | 0.83 | THRB (0.36) | THRBTSHRACHE | |
| SCHEMBL6253284 | 0.83 | THRB (0.42) | THRBTSHRALDH1A1ACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9662809-B2 | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160236379-A1 | Methods and Materials for Fabricating Laminate Nanomolds and Nanoparticles Therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2016-08-18 | — | — | US | disclosed |
| US-9340001-B2 | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-20160038418-A1 | NANOPARTICLE FABRICATION METHODS, SYSTEMS, AND MATERIALS | NATIONAL SCIENCE FOUNDATION | 2016-02-11 | — | — | US | disclosed |
| US-8439666-B2 | Methods and materials for fabricating laminate nanomolds and nanoparticles therefrom | LIQUIDIA TECHNOLOGIES, INC. (US) | 2013-05-14 | — | — | US | disclosed |
| US-8158728-B2 | Methods and materials for fabricating microfluidic devices | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160038418-A1 | NANOPARTICLE FABRICATION METHODS, SYSTEMS, AND MATERIALS | TTN, TAGLN2, TLN1 | THRB 2627/4885TSHR 840/4885ALDH1A1 1111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.