SCHEMBL8583501

SCHEMBL8583501

Oc1ccc(N(O)c2ccccc2)c(O)c1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.44
EIF4H Q15056 2/20 0.44
ALDH1A1 P00352 4/20 0.38
MEN1 O00255 4/20 0.38
GAA P10253 4/20 0.38
KMT2A Q03164 4/20 0.38
KDM4E B2RXH2 3/20 0.38
MAPT P10636 3/20 0.38
HPGD P15428 3/20 0.35
LMNA P02545 2/20 0.35
NSD2 O96028 1/20 0.35
G6PD P11413 1/20 0.35
MAPK1 P28482 1/20 0.35
MPI P34949 1/20 0.35
HTT P42858 1/20 0.35
BLM P54132 1/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
MCL1 Q07820 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8580333 0.83 ALDH1A1 (0.44) POLBEIF4HALDH1A1MEN1GAA
SCHEMBL8582837 0.81 POLB (0.46) POLBEIF4HALDH1A1MEN1GAA
SCHEMBL3809204 0.76 ALDH1A1 (0.41) POLBEIF4HALDH1A1MEN1GAA
SCHEMBL1032263 0.71 NPSR1 (0.48) POLBALDH1A1MEN1GAAKMT2A
SCHEMBL30435253 0.69 NPSR1 (0.46) POLBALDH1A1MEN1GAAKMT2A
SCHEMBL2385266 0.68 POLB (0.39) POLBEIF4HALDH1A1MEN1GAA
SCHEMBL8582938 0.67 POLB (0.37) POLBEIF4HALDH1A1MEN1GAA
Ethane SCHEMBL9330415 0.66 NPSR1 (0.43) ALDH1A1MEN1GAAKMT2AMAPT
SCHEMBL29256096 0.66 CA12 (0.50) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL16962795 0.65 CYP3A4 (0.39) ALDH1A1GAAKDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102559207-B Liquid crystal aligning agent, polymer, method for producing polymer, liquid crystal alignment film and liquid crystal display device JSR CORP 2015-01-14 CN disclosed
CN-102559207-A Liquid crystal aligning agent, polymer, method for producing polymer, liquid crystal alignment film and liquid crystal display device JSR CORP 2012-07-11 CN disclosed
US-5756650-A COMPOSITION COMPRISING POLYAMIC ACID, CURE ACCELERATOR SELECTED FROM GROUP CONSISTING OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AMINO ACID COMPOUND, AROMATIC COMPOUND HAVING TWO OR MORE HYDROXYL GROUPS KABUSHIKI KAISHA TOSHIBA (JP) 1998-05-26 US disclosed