SCHEMBL2385266

SCHEMBL2385266

Cc1c(N(c2ccccc2)c2ccccc2)ccc(O)c1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.39
EIF4H Q15056 1/20 0.39
EP300 Q09472 1/20 0.36
KAT2B Q92831 1/20 0.36
KAT8 Q9H7Z6 1/20 0.36
ESR1 P03372 2/20 0.36
TRPA1 O75762 1/20 0.34
ESR2 Q92731 1/20 0.34
KDM4E B2RXH2 4/20 0.33
MAPT P10636 4/20 0.33
ALDH1A1 P00352 4/20 0.33
GAA P10253 3/20 0.33
CYP2D6 P10635 2/20 0.33
PKM P14618 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
RECQL P46063 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8582837 0.82 POLB (0.46) POLBEIF4HEP300KAT2BKAT8
SCHEMBL18209352 0.74 ALDH1A1 (0.37) KDM4EMAPTALDH1A1CYP2D6TDP1
SCHEMBL5245029 0.74 ALDH1A1 (0.37) KDM4EMAPTALDH1A1CYP2D6TDP1
SCHEMBL5881115 0.74 ALDH1A1 (0.46) POLBEIF4HTRPA1KDM4EMAPT
SCHEMBL16067292 0.73 TRPA1 (0.45) POLBESR1TRPA1KDM4EMAPT
SCHEMBL6941899 0.73 HTT (0.35) ESR1KDM4EMAPTALDH1A1GAA
SCHEMBL8762568 0.73 EP300 (0.47) EP300KAT2BKAT8ESR1TRPA1
SCHEMBL29428918 0.70 CYP2D6 (0.41) POLBEIF4HEP300KAT2BKAT8
SCHEMBL28463357 0.70 CYP2D6 (0.41) POLBEIF4HEP300KAT2BKAT8
SCHEMBL184114 0.70 ALDH1A1 (0.43) POLBKDM4EMAPTALDH1A1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101266451-B Cleaning unit, process cartridge, and image forming apparatus using the same RICOH CO LTD 2012-06-06 CN disclosed
US-8027628-B2 Cleaning device, process cartridge, and image forming apparatus RICOH COMPANY, LTD. (JP) 2011-09-27 US disclosed
US-7862969-B2 Image bearing member and image forming method using thereof, and image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2011-01-04 US disclosed
CN-101034264-B Image bearing member and image forming method using thereof, and image forming apparatus and process cartridge RICOH KK 2010-12-01 CN disclosed
CN-1885180-B Image forming method, and image forming apparatus and process cartridge using the image forming method RICOH KK 2010-06-02 CN disclosed
CN-100593757-C Cover layer for electrophotographic printing roller SENSIENT IMAGING TECHNOLOGIES 2010-03-10 CN disclosed
CN-101430532-A Cleaning device, method of manufacturing the cleaning device, and process unit and image forming apparatus using same RICOH KK (JP) 2009-05-13 CN disclosed
US-20090035038-A1 CLEANING DEVICE, IMAGE CARRIER UNIT, AND IMAGE FORMING APPARATUS RICOH COMPANY, LIMITED (JP) 2009-02-05 US disclosed
CN-101315525-A Photoconductor XEROX CORP (US) 2008-12-03 CN disclosed
US-20080286020-A1 CLEANING DEVICE, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS WATANABE KAZUHIKO 2008-11-20 US disclosed
US-7415238-B2 Cleaning device, process cartridge, and image forming apparatus that include a blade that is pressed against a surface of a rotating member at a surface pressure of 2.0 MPa or more RICOH COMPANY, LTD. (JP) 2008-08-19 US disclosed
CN-101164017-A Covering layer for electrophotographic printing rollers SENSIENT IMAGING TECHNOLOGIES (DE) 2008-04-16 CN disclosed
US-20070212625-A1 IMAGE BEARING MEMBER AND IMAGE FORMING METHOD USING THEREOF, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-09-13 US disclosed
US-20070212139-A1 IMAGE FORMING APPARATUS, PROCESS UNIT, AND CLEANING DEVICE RICOH CO., LTD. (JP) 2007-09-13 US disclosed
CN-101034264-A Image bearing member and image forming method using thereof, and image forming apparatus and process cartridge RICOH KK (JP) 2007-09-12 CN disclosed
US-20060099016-A1 Cleaning device, process cartridge, and image forming apparatus RICOH COMPANY, LTD. (JP) 2006-05-11 US disclosed
CN-1217242-C Static copy photo receptor KONISHIROKU PHOTO IND (JP) 2005-08-31 CN disclosed
US-20040013442-A1 Electrophotographic image forming apparatus RICOH COMPANY, LTD. (JP) 2004-01-22 US disclosed
US-20030147670-A1 Electrostatic images using toner; crosslinked polysiloxane ASANO MASAO (JP) 2003-08-07 US disclosed
CN-1252541-A Static copy photo receptor KONISHIROKU PHOTO IND (JP) 2000-05-10 CN disclosed