Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526214 | 0.74 | HTR2A (0.35) | KDM4EALDH1A1MAPT | |
| SCHEMBL8583802 | 0.72 | KDM4E (0.48) | KDM4EHSD17B10GAAALDH1A1MAPK1 | |
| SCHEMBL8528250 | 0.70 | CA2 (0.35) | GAAALDH1A1MAPT | |
| SCHEMBL8526423 | 0.69 | SLC1A3 (0.39) | KDM4EALDH1A1MAPT | |
| SCHEMBL9202601 | 0.68 | HTR2A (0.35) | KDM4EALDH1A1MAPT | |
| SCHEMBL8526317 | 0.68 | HTR2A (0.35) | KDM4EALDH1A1MAPT | |
| SCHEMBL9199436 | 0.68 | HTR2A (0.35) | KDM4EALDH1A1MAPT | |
| SCHEMBL9199405 | 0.68 | HTR2A (0.35) | KDM4EALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL9272122 | 0.67 | HTR2A (0.33) | — | |
| Trifluoroacetic Acid SCHEMBL9269121 | 0.67 | HTR2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |