Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 4/20 | 0.35 |
| ▸ | MC3R | P41968 | 4/20 | 0.35 |
| ▸ | MC5R | P33032 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | EPOR | P19235 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202601 | 0.74 | HTR2A (0.35) | MC4RKDM4EMAPTNPSR1ALDH1A1 | |
| SCHEMBL9199436 | 0.74 | HTR2A (0.35) | MC4RKDM4EMAPTNPSR1ALDH1A1 | |
| SCHEMBL9199405 | 0.74 | HTR2A (0.35) | MC4RKDM4EMAPTNPSR1ALDH1A1 | |
| SCHEMBL8526317 | 0.74 | HTR2A (0.35) | MC4RKDM4EMAPTNPSR1ALDH1A1 | |
| SCHEMBL9574165 | 0.74 | EPOR (0.46) | SLC1A3SLC1A1EPORALDH1A1PRSS1 | |
| SCHEMBL4852056 | 0.74 | EPOR (0.46) | SLC1A3SLC1A1EPORALDH1A1PRSS1 | |
| SCHEMBL10477497 | 0.74 | EPOR (0.46) | SLC1A3SLC1A1EPORALDH1A1PRSS1 | |
| SCHEMBL10432184 | 0.73 | MC4R (0.47) | TGM2MC4REPORHDAC1HDAC2 | |
| SCHEMBL8526425 | 0.73 | TGM2 (0.47) | TGM2HDAC1HDAC2PRSS1PRSS2 | |
| SCHEMBL8525693 | 0.72 | CPB2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |