Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583888 | 1.00 | HTR7 (0.33) | HTR7HDAC3HDAC1HDAC2GAA | |
| SCHEMBL8585469 | 0.84 | SMN1; SMN2 (0.38) | HDAC3HDAC1HDAC2 | |
| SCHEMBL8585468 | 0.84 | SMN1; SMN2 (0.38) | HDAC3HDAC1HDAC2 | |
| SCHEMBL1661860 | 0.73 | NFE2L2 (0.42) | HTR7TRPA1 | |
| SCHEMBL7773893 | 0.72 | — | — | |
| SCHEMBL7773897 | 0.72 | — | — | |
| SCHEMBL8584493 | 0.71 | SMN1; SMN2 (0.37) | HDAC3HDAC1HDAC2 | |
| SCHEMBL8880578 | 0.71 | SMN1; SMN2 (0.37) | HDAC3HDAC1HDAC2 | |
| SCHEMBL4245756 | 0.69 | — | — | |
| SCHEMBL4245758 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998020878-A1 | 5-[φ-(SUBSTITUTED ARYL)ALKENYLENE AND ALKYNYLENE]-2,4-DIAMINOPYRIMIDINES AS PESTICIDES | FMC CORPORATION (US) | 1998-05-22 | — | — | WO | disclosed |
| US-5696259-A | 2,4-diamino-5-iodopyrimidines useful as pesticide intermediates | FMC CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| US-5622954-A | INSECTICIDE | FMC CORPORATION (US) | 1997-04-22 | — | — | US | disclosed |