Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8585228 | 0.95 | SCN9A (0.40) | GAAHTTSLC9A1KDM4EHSD17B10 | |
| SCHEMBL8582854 | 0.95 | KDM4E (0.40) | GAAHTTSLC9A1KDM4EHSD17B10 | |
| SCHEMBL8580817 | 0.93 | ALDH1A1 (0.42) | GAAHTTSLC9A1KDM4EHSD17B10 | |
| SCHEMBL8584023 | 0.84 | SLC9A1 (0.50) | SLC9A1KDM4EHSD17B10PDK2PDK4 | |
| SCHEMBL8578049 | 0.83 | ALDH1A1 (0.43) | SLC9A1HSD17B10ALDH1A1TSHRHPGD | |
| SCHEMBL8585395 | 0.83 | SLC9A1 (0.39) | GAASLC9A1KDM4EHSD17B10KMT2A | |
| SCHEMBL8583639 | 0.82 | GAA (0.36) | GAAHTTKDM4EHSD17B10MEN1 | |
| SCHEMBL8581635 | 0.82 | SLC9A1 (0.41) | SLC9A1KDM4ECA1CA2ALDH1A1 | |
| SCHEMBL8532879 | 0.81 | SLC9A1 (0.58) | SLC9A1 | |
| SCHEMBL8585098 | 0.80 | GAA (0.39) | GAASLC9A1KDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |